Cargando…
Single Point Mutations Result in the Miss-Sorting of Glut4 to a Novel Membrane Compartment Associated with Stress Granule Proteins
Insulin increases cellular glucose uptake and metabolism in the postprandial state by acutely stimulating the translocation of the Glut4 glucose transporter from intracellular membrane compartments to the cell surface in muscle and fat cells. The intracellular targeting of Glut4 is dictated by speci...
Autores principales: | Song, XiaoMei, Lichti, Cheryl F., Townsend, R. Reid, Mueckler, Mike |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3713040/ https://www.ncbi.nlm.nih.gov/pubmed/23874650 http://dx.doi.org/10.1371/journal.pone.0068516 |
Ejemplares similares
-
Ligand-Induced Movements of Inner Transmembrane Helices of Glut1 Revealed by Chemical Cross-Linking of Di-Cysteine Mutants
por: Mueckler, Mike, et al.
Publicado: (2012) -
GLUT4 Traffic through an ESCRT-III-Dependent Sorting Compartment in Adipocytes
por: Koumanov, Françoise, et al.
Publicado: (2012) -
Dynamic GLUT4 sorting through a syntaxin-6 compartment in muscle cells is derailed by insulin resistance-causing ceramide
por: Foley, Kevin P., et al.
Publicado: (2014) -
Protein sorting to intracellular compartments
por: Jackson, Catherine L., et al.
Publicado: (2015) -
Protein targeting via the "constitutive-like" secretory pathway in isolated pancreatic islets: passive sorting in the immature granule compartment
Publicado: (1992)