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The cell death protease Kex1p is essential for hypochlorite-induced apoptosis in yeast

Following microbial pathogen invasion, the human immune system of activated phagocytes generates and releases the potent oxidant hypochlorous acid (HOCl), which contributes to the killing of menacing microorganisms. Though tightly controlled, HOCl generation by the myeloperoxidase-hydrogen peroxide-...

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Detalles Bibliográficos
Autores principales: Carmona-Gutierrez, Didac, Alavian-Ghavanini, Ali, Habernig, Lukas, Bauer, Maria Anna, Hammer, Astrid, Rossmann, Christine, Zimmermann, Andreas S., Ruckenstuhl, Christoph, Büttner, Sabrina, Eisenberg, Tobias, Sattler, Wolfgang, Malle, Ernst, Madeo, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3713129/
https://www.ncbi.nlm.nih.gov/pubmed/23656787
http://dx.doi.org/10.4161/cc.24801