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Glucocorticoid-Dependent Hippocampal Transcriptome in Male Rats: Pathway-Specific Alterations With Aging

Although glucocorticoids (GCs) are known to exert numerous effects in the hippocampus, their chronic regulatory functions remain poorly understood. Moreover, evidence is inconsistent regarding the long-standing hypothesis that chronic GC exposure promotes brain aging/Alzheimer disease. Here, we adre...

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Detalles Bibliográficos
Autores principales: Chen, Kuey-Chu, Blalock, Eric M., Curran-Rauhut, Meredith A., Kadish, Inga, Blalock, Susan J., Brewer, Lawrence, Porter, Nada M., Landfield, Philip W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3713214/
https://www.ncbi.nlm.nih.gov/pubmed/23736296
http://dx.doi.org/10.1210/en.2013-1139