Cargando…
New method of peptide cleavage based on Edman degradation
A straightforward cleavage method for N- acylated peptides based on the phenylthiohydantoin (PTH) formation is presented. The procedure could be applied to acid-stable resins, such as TentaGel HL–NH[Formula: see text] . We designed a cleavable linker that consists of a lysine residue with the [Formu...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3713267/ https://www.ncbi.nlm.nih.gov/pubmed/23690169 http://dx.doi.org/10.1007/s11030-013-9453-y |