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New method of peptide cleavage based on Edman degradation
A straightforward cleavage method for N- acylated peptides based on the phenylthiohydantoin (PTH) formation is presented. The procedure could be applied to acid-stable resins, such as TentaGel HL–NH[Formula: see text] . We designed a cleavable linker that consists of a lysine residue with the [Formu...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Netherlands
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3713267/ https://www.ncbi.nlm.nih.gov/pubmed/23690169 http://dx.doi.org/10.1007/s11030-013-9453-y |