Clinical Significance of HER-2 Splice Variants in Breast Cancer Progression and Drug Resistance

Overexpression of human epidermal growth factor receptor (HER-2) occurs in 20–30% of breast cancers and confers survival and proliferative advantages on the tumour cells making HER-2 an ideal therapeutic target for drugs like Herceptin. Continued delineation of tumour biology has identified splice v...

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Detalles Bibliográficos
Autores principales: Jackson, Claire, Browell, David, Gautrey, Hannah, Tyson-Capper, Alison
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3713377/
https://www.ncbi.nlm.nih.gov/pubmed/23935627
http://dx.doi.org/10.1155/2013/973584

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3713377/
https://www.ncbi.nlm.nih.gov/pubmed/23935627
http://dx.doi.org/10.1155/2013/973584

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