Cargando…

ATR acts stage specifically to regulate multiple aspects of mammalian meiotic silencing

In mammals, homologs that fail to synapse during meiosis are transcriptionally inactivated. This process, meiotic silencing, drives inactivation of the heterologous XY bivalent in male germ cells (meiotic sex chromosome inactivation [MSCI]) and is thought to act as a meiotic surveillance mechanism....

Descripción completa

Detalles Bibliográficos
Autores principales: Royo, Hélène, Prosser, Haydn, Ruzankina, Yaroslava, Mahadevaiah, Shantha K., Cloutier, Jeffrey M., Baumann, Marek, Fukuda, Tomoyuki, Höög, Christer, Tóth, Attila, de Rooij, Dirk G., Bradley, Allan, Brown, Eric J., Turner, James M.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3713429/
https://www.ncbi.nlm.nih.gov/pubmed/23824539
http://dx.doi.org/10.1101/gad.219477.113