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ATR acts stage specifically to regulate multiple aspects of mammalian meiotic silencing
In mammals, homologs that fail to synapse during meiosis are transcriptionally inactivated. This process, meiotic silencing, drives inactivation of the heterologous XY bivalent in male germ cells (meiotic sex chromosome inactivation [MSCI]) and is thought to act as a meiotic surveillance mechanism....
Autores principales: | Royo, Hélène, Prosser, Haydn, Ruzankina, Yaroslava, Mahadevaiah, Shantha K., Cloutier, Jeffrey M., Baumann, Marek, Fukuda, Tomoyuki, Höög, Christer, Tóth, Attila, de Rooij, Dirk G., Bradley, Allan, Brown, Eric J., Turner, James M.A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3713429/ https://www.ncbi.nlm.nih.gov/pubmed/23824539 http://dx.doi.org/10.1101/gad.219477.113 |
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