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Structural integrity of the substantia nigra and subthalamic nucleus predicts flexibility of instrumental learning in older-age individuals

Flexible instrumental learning is required to harness the appropriate behaviors to obtain rewards and to avoid punishments. The precise contribution of dopaminergic midbrain regions (substantia nigra/ventral tegmental area [SN/VTA]) to this form of behavioral adaptation remains unclear. Normal aging...

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Detalles Bibliográficos
Autores principales: Chowdhury, Rumana, Guitart-Masip, Marc, Lambert, Christian, Dolan, Raymond J., Düzel, Emrah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3713434/
https://www.ncbi.nlm.nih.gov/pubmed/23623600
http://dx.doi.org/10.1016/j.neurobiolaging.2013.03.030