High-Yield Soluble Expression and Simple Purification of the Antimicrobial Peptide OG2 Using the Intein System in Escherichia coli

OG2 is a modified antimicrobial peptide, that is, derived from the frog peptide Palustrin-OG1. It has high antimicrobial activity and low cytotoxicity, and it is therefore promising as a therapeutic agent. Both prokaryotic (Escherichia coli) and eukaryotic (Pichia pastoris) production host systems w...

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Detalles Bibliográficos
Autores principales: Xie, Yong-Gang, Han, Fei-Fei, Luan, Chao, Zhang, Hai-Wen, Feng, Jie, Choi, Young-Jun, Groleau, Denis, Wang, Yi-Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3713655/
https://www.ncbi.nlm.nih.gov/pubmed/23936842
http://dx.doi.org/10.1155/2013/754319

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3713655/
https://www.ncbi.nlm.nih.gov/pubmed/23936842
http://dx.doi.org/10.1155/2013/754319

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