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Attenuating gene expression (AGE) for vaccine development

Live attenuated vaccines are adept in stimulating protective immunity. Methods for generating such vaccines have largely adopted strategies used with Salmonella enterica. Yet, when similar strategies were tested in other gram-negative bacteria, the virulence factors or genes responsible to incapacit...

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Detalles Bibliográficos
Autores principales: Pascual, David W, Suo, Zhiyong, Cao, Ling, Avci, Recep, Yang, Xinghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3714130/
https://www.ncbi.nlm.nih.gov/pubmed/23652809
http://dx.doi.org/10.4161/viru.24886