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Immunomodulator Clarithromycin Enhances Mucosal and Systemic Immune Responses and Reduces Re-Infection Rate in Pediatric Patients with Influenza Treated with Antiviral Neuraminidase Inhibitors: A Retrospective Analysis

BACKGROUND/AIMS: Treatment with antiviral neuraminidase inhibitors suppresses influenza viral replication and antigen production, resulting in marked attenuation of mucosal immunity and mild suppression of systemic immunity in mice. This study investigated the effects of immunomodulator clarithromyc...

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Detalles Bibliográficos
Autores principales: Shinahara, Wakako, Takahashi, Etsuhisa, Sawabuchi, Takako, Arai, Masaru, Hirotsu, Nobuo, Takasaki, Yoshio, Shindo, Shizuo, Shibao, Kyoko, Yokoyama, Takashi, Nishikawa, Kiyoshi, Mino, Masahiro, Iwaya, Minako, Yamashita, Yuji, Suzuki, Satoshi, Mizuno, Dai, Kido, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3714257/
https://www.ncbi.nlm.nih.gov/pubmed/23875018
http://dx.doi.org/10.1371/journal.pone.0070060