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Immunomodulator Clarithromycin Enhances Mucosal and Systemic Immune Responses and Reduces Re-Infection Rate in Pediatric Patients with Influenza Treated with Antiviral Neuraminidase Inhibitors: A Retrospective Analysis
BACKGROUND/AIMS: Treatment with antiviral neuraminidase inhibitors suppresses influenza viral replication and antigen production, resulting in marked attenuation of mucosal immunity and mild suppression of systemic immunity in mice. This study investigated the effects of immunomodulator clarithromyc...
Autores principales: | Shinahara, Wakako, Takahashi, Etsuhisa, Sawabuchi, Takako, Arai, Masaru, Hirotsu, Nobuo, Takasaki, Yoshio, Shindo, Shizuo, Shibao, Kyoko, Yokoyama, Takashi, Nishikawa, Kiyoshi, Mino, Masahiro, Iwaya, Minako, Yamashita, Yuji, Suzuki, Satoshi, Mizuno, Dai, Kido, Hiroshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3714257/ https://www.ncbi.nlm.nih.gov/pubmed/23875018 http://dx.doi.org/10.1371/journal.pone.0070060 |
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