ERK Positive Feedback Regulates a Widespread Network of Tyrosine Phosphorylation Sites across Canonical T Cell Signaling and Actin Cytoskeletal Proteins in Jurkat T Cells

Competing positive and negative signaling feedback pathways play a critical role in tuning the sensitivity of T cell receptor activation by creating an ultrasensitive, bistable switch to selectively enhance responses to foreign ligands while suppressing signals from self peptides. In response to T c...

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Detalles Bibliográficos
Autores principales: Helou, Ynes A., Nguyen, Vinh, Beik, Samantha P., Salomon, Arthur R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3714263/
https://www.ncbi.nlm.nih.gov/pubmed/23874979
http://dx.doi.org/10.1371/journal.pone.0069641

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3714263/
https://www.ncbi.nlm.nih.gov/pubmed/23874979
http://dx.doi.org/10.1371/journal.pone.0069641

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