The N276 Glycosylation Site Is Required for HIV-1 Neutralization by the CD4 Binding Site Specific HJ16 Monoclonal Antibody

Immunogen design for HIV-1 vaccines could be based on epitope identification of naturally occurring neutralizing antibodies in infected patients. A tier 2 neutralizing monoclonal antibody (mAb), HJ16 recognizes a new epitope in the CD4 binding site (CD4bs) region that only partially overlaps with th...

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Detalles Bibliográficos
Autores principales: Balla-Jhagjhoorsingh, Sunita S., Corti, Davide, Heyndrickx, Leo, Willems, Elisabeth, Vereecken, Katleen, Davis, David, Vanham, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3714269/
https://www.ncbi.nlm.nih.gov/pubmed/23874792
http://dx.doi.org/10.1371/journal.pone.0068863

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3714269/
https://www.ncbi.nlm.nih.gov/pubmed/23874792
http://dx.doi.org/10.1371/journal.pone.0068863

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