Lubiprostone Increases Small Intestinal Smooth Muscle Contractions Through a Prostaglandin E Receptor 1 (EP(1))-mediated Pathway

BACKGROUND/AIMS: Lubiprostone, a chloride channel type 2 (ClC-2) activator, was thought to treat constipation by enhancing intestinal secretion. It has been associated with increased intestinal transit and delayed gastric emptying. Structurally similar to prostones with up to 54% prostaglandin E(2)...

Descripción completa

Detalles Bibliográficos
Autores principales: Chan, Walter W, Mashimo, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Neurogastroenterology and Motility 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3714408/
https://www.ncbi.nlm.nih.gov/pubmed/23875097
http://dx.doi.org/10.5056/jnm.2013.19.3.312

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3714408/
https://www.ncbi.nlm.nih.gov/pubmed/23875097
http://dx.doi.org/10.5056/jnm.2013.19.3.312

Ejemplares similares