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Pramipexole in patients with early Parkinson's disease (PROUD): a randomised delayed-start trial
BACKGROUND: In models of dopaminergic neuronal loss, the dopamine agonist pramipexole has exhibited neuroprotective properties. The Pramipexole On Underlying Disease (PROUD) study was designed to identify whether early versus delayed pramipexole initiation has clinical and neuroimaging benefits in p...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lancet Pub. Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3714436/ https://www.ncbi.nlm.nih.gov/pubmed/23726851 http://dx.doi.org/10.1016/S1474-4422(13)70117-0 |