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Thrombin promotes epithelial ovarian cancer cell invasion by inducing epithelial-mesenchymal transition

OBJECTIVE: Over-expression of thrombin in ovarian cancer cells is associated with poor prognosis. In this study, we investigated the role of thrombin in inducing epithelial-mesenchymal transition (EMT) in SKOV3 epithelial ovarian cancer cells. METHODS: After thrombin treatment SKOV3 cells were subje...

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Detalles Bibliográficos
Autores principales: Zhong, Yi-Cun, Zhang, Ting, Di, Wen, Li, Wei-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Asian Society of Gynecologic Oncology; Korean Society of Gynecologic Oncology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3714465/
https://www.ncbi.nlm.nih.gov/pubmed/23875077
http://dx.doi.org/10.3802/jgo.2013.24.3.265