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Selective cyclooxygenase inhibitors increase paclitaxel sensitivity in taxane-resistant ovarian cancer by suppressing P-glycoprotein expression

OBJECTIVE: The purpose of this study was to investigate whether selective cyclooxygenase (COX) inhibitors promote paclitaxel-induced apoptosis in taxane-resistant ovarian cancer cells by suppressing MDR1/P-glycoprotein (P-gp) expression. METHODS: Taxane-resistant ovarian cancer cells were cultured w...

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Detalles Bibliográficos
Autores principales: Lee, Jung-Pil, Hahn, Ho-Suap, Hwang, Soo-Jin, Choi, Ji-Young, Park, Jong-Sup, Lee, In-Ho, Kim, Tae-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Asian Society of Gynecologic Oncology; Korean Society of Gynecologic Oncology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3714466/
https://www.ncbi.nlm.nih.gov/pubmed/23875078
http://dx.doi.org/10.3802/jgo.2013.24.3.273