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Glucagon-Like Peptide 1 Reduces Endothelial Dysfunction, Inflammation, and Oxidative Stress Induced by Both Hyperglycemia and Hypoglycemia in Type 1 Diabetes

OBJECTIVE: Hyperglycemia and hypoglycemia currently are considered risk factors for cardiovascular disease in type 1diabetes. Both acute hyperglycemia and hypoglycemia induce endothelial dysfunction and inflammation, raising the oxidative stress. Glucagon-like peptide 1 (GLP-1) has antioxidant prope...

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Detalles Bibliográficos
Autores principales: Ceriello, Antonio, Novials, Anna, Ortega, Emilio, Canivell, Silvia, La Sala, Lucia, Pujadas, Gemma, Esposito, Katherine, Giugliano, Dario, Genovese, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3714509/
https://www.ncbi.nlm.nih.gov/pubmed/23564922
http://dx.doi.org/10.2337/dc12-2469