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Proinsulin/Insulin Autoantibodies Measured With Electrochemiluminescent Assay Are the Earliest Indicator of Prediabetic Islet Autoimmunity

OBJECTIVE: We evaluated a novel electrochemiluminescent assay for insulin/proinsulin autoantibodies (ECL-IAA) as a new marker of the onset of islet autoimmunity and as a predictor of type 1 diabetes. RESEARCH DESIGN AND METHODS: The Diabetes Autoimmunity Study in the Young (DAISY) prospectively foll...

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Detalles Bibliográficos
Autores principales: Yu, Liping, Dong, Fran, Miao, Dongmei, Fouts, Alexandra R., Wenzlau, Janet M., Steck, Andrea K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3714529/
https://www.ncbi.nlm.nih.gov/pubmed/23423694
http://dx.doi.org/10.2337/dc12-2245