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Competitive Interactions Eliminate Unfit Embryonic Stem Cells at the Onset of Differentiation
A fundamental question in developmental biology is whether there are mechanisms to detect stem cells with mutations that, although not adversely affecting viability, would compromise their ability to contribute to further development. Here, we show that cell competition is a mechanism regulating the...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3714589/ https://www.ncbi.nlm.nih.gov/pubmed/23867226 http://dx.doi.org/10.1016/j.devcel.2013.06.012 |