Competitive Interactions Eliminate Unfit Embryonic Stem Cells at the Onset of Differentiation

A fundamental question in developmental biology is whether there are mechanisms to detect stem cells with mutations that, although not adversely affecting viability, would compromise their ability to contribute to further development. Here, we show that cell competition is a mechanism regulating the...

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Detalles Bibliográficos
Autores principales: Sancho, Margarida, Di-Gregorio, Aida, George, Nancy, Pozzi, Sara, Sánchez, Juan Miguel, Pernaute, Barbara, Rodríguez, Tristan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3714589/
https://www.ncbi.nlm.nih.gov/pubmed/23867226
http://dx.doi.org/10.1016/j.devcel.2013.06.012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3714589/
https://www.ncbi.nlm.nih.gov/pubmed/23867226
http://dx.doi.org/10.1016/j.devcel.2013.06.012

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