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Elimination of Unfit Cells Maintains Tissue Health and Prolongs Lifespan

Viable yet damaged cells can accumulate during development and aging. Although eliminating those cells may benefit organ function, identification of this less fit cell population remains challenging. Previously, we identified a molecular mechanism, based on “fitness fingerprints” displayed on cell m...

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Detalles Bibliográficos
Autores principales: Merino, Marisa M., Rhiner, Christa, Lopez-Gay, Jesus M., Buechel, David, Hauert, Barbara, Moreno, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4313366/
https://www.ncbi.nlm.nih.gov/pubmed/25601460
http://dx.doi.org/10.1016/j.cell.2014.12.017