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Cell-Type-Specific Profiling of Gene Expression and Chromatin Binding without Cell Isolation: Assaying RNA Pol II Occupancy in Neural Stem Cells

Cell-type-specific transcriptional profiling often requires the isolation of specific cell types from complex tissues. We have developed “TaDa,” a technique that enables cell-specific profiling without cell isolation. TaDa permits genome-wide profiling of DNA- or chromatin-binding proteins without c...

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Detalles Bibliográficos
Autores principales: Southall, Tony D., Gold, Katrina S., Egger, Boris, Davidson, Catherine M., Caygill, Elizabeth E., Marshall, Owen J., Brand, Andrea H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3714590/
https://www.ncbi.nlm.nih.gov/pubmed/23792147
http://dx.doi.org/10.1016/j.devcel.2013.05.020