The role of reactive oxygen species and proinflammatory cytokines in type 1 diabetes pathogenesis

Type 1 diabetes (T1D) is a T cell–mediated autoimmune disease characterized by the destruction of insulin-secreting pancreatic β cells. In humans with T1D and in nonobese diabetic (NOD) mice (a murine model for human T1D), autoreactive T cells cause β-cell destruction, as transfer or deletion of the...

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Detalles Bibliográficos
Autores principales: Padgett, Lindsey E, Broniowska, Katarzyna A, Hansen, Polly A, Corbett, John A, Tse, Hubert M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715103/
https://www.ncbi.nlm.nih.gov/pubmed/23323860
http://dx.doi.org/10.1111/j.1749-6632.2012.06826.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715103/
https://www.ncbi.nlm.nih.gov/pubmed/23323860
http://dx.doi.org/10.1111/j.1749-6632.2012.06826.x

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