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Metabolic Profiling Predicts Response to Anti–Tumor Necrosis Factor α Therapy in Patients With Rheumatoid Arthritis

OBJECTIVE: Anti–tumor necrosis factor (anti-TNF) therapies are highly effective in rheumatoid arthritis (RA) and psoriatic arthritis (PsA), but a significant number of patients exhibit only a partial or no therapeutic response. Inflammation alters local and systemic metabolism, and TNF plays a role...

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Detalles Bibliográficos
Autores principales: Kapoor, Sabrina R, Filer, Andrew, Fitzpatrick, Martin A, Fisher, Benjamin A, Taylor, Peter C, Buckley, Christopher D, McInnes, Iain B, Raza, Karim, Young, Stephen P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715109/
https://www.ncbi.nlm.nih.gov/pubmed/23460124
http://dx.doi.org/10.1002/art.37921