Association of plasma uric acid with ischaemic heart disease and blood pressure: mendelian randomisation analysis of two large cohorts

Objectives To assess the associations between both uric acid levels and hyperuricaemia, with ischaemic heart disease and blood pressure, and to explore the potentially confounding role of body mass index. Design Mendelian randomisation analysis, using variation at specific genes (SLC2A9 (rs7442295)...

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Detalles Bibliográficos
Autores principales: Palmer, Tom M, Nordestgaard, Børge G, Benn, Marianne, Tybjærg-Hansen, Anne, Davey Smith, George, Lawlor, Debbie A, Timpson, Nicholas J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group Ltd. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715134/
https://www.ncbi.nlm.nih.gov/pubmed/23869090
http://dx.doi.org/10.1136/bmj.f4262