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Mechanism of HIV-1 Virion Entrapment by Tetherin

Tetherin, an interferon-inducible membrane protein, inhibits the release of nascent enveloped viral particles from the surface of infected cells. However, the mechanisms underlying virion retention have not yet been fully delineated. Here, we employ biochemical assays and engineered tetherin protein...

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Detalles Bibliográficos
Autores principales: Venkatesh, Siddarth, Bieniasz, Paul D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715405/
https://www.ncbi.nlm.nih.gov/pubmed/23874200
http://dx.doi.org/10.1371/journal.ppat.1003483