Defective Repair of Oxidative Base Lesions by the DNA Glycosylase Nth1 Associates with Multiple Telomere Defects

Telomeres are chromosome end structures and are essential for maintenance of genome stability. Highly repetitive telomere sequences appear to be susceptible to oxidative stress-induced damage. Oxidation may therefore have a severe impact on telomere integrity and function. A wide spectrum of oxidati...

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Detalles Bibliográficos
Autores principales: Vallabhaneni, Haritha, O'Callaghan, Nathan, Sidorova, Julia, Liu, Yie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715427/
https://www.ncbi.nlm.nih.gov/pubmed/23874233
http://dx.doi.org/10.1371/journal.pgen.1003639

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715427/
https://www.ncbi.nlm.nih.gov/pubmed/23874233
http://dx.doi.org/10.1371/journal.pgen.1003639

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