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EphrinA2 Regulates Clathrin Mediated KSHV Endocytosis in Fibroblast Cells by Coordinating Integrin-Associated Signaling and c-Cbl Directed Polyubiquitination

Kaposi's sarcoma-associated herpesvirus (KSHV) interacts with human dermal endothelial cell surface tyrosine kinase EphrinA2 (EphA2) and integrins (α3β1 and αVβ3) in the lipid raft (LR) region, and EphA2 regulates macropinocytic virus entry by coordinating integrin-c-Cbl associated signaling. I...

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Detalles Bibliográficos
Autores principales: Dutta, Dipanjan, Chakraborty, Sayan, Bandyopadhyay, Chirosree, Valiya Veettil, Mohanan, Ansari, Mairaj Ahmed, Singh, Vivek Vikram, Chandran, Bala
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715429/
https://www.ncbi.nlm.nih.gov/pubmed/23874206
http://dx.doi.org/10.1371/journal.ppat.1003510