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Yeast Pol4 Promotes Tel1-Regulated Chromosomal Translocations

DNA double-strand breaks (DSBs) are one of the most dangerous DNA lesions, since their erroneous repair by nonhomologous end-joining (NHEJ) can generate harmful chromosomal rearrangements. PolX DNA polymerases are well suited to extend DSB ends that cannot be directly ligated due to their particular...

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Detalles Bibliográficos
Autores principales: Ruiz, Jose F., Pardo, Benjamin, Sastre-Moreno, Guillermo, Aguilera, Andrés, Blanco, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715435/
https://www.ncbi.nlm.nih.gov/pubmed/23874240
http://dx.doi.org/10.1371/journal.pgen.1003656