Induction of Regulatory T Cells by High-Dose gp96 Suppresses Murine Liver Immune Hyperactivation

Immunization with high-dose heat shock protein gp96, an endoplasmic reticulum counterpart of the Hsp90 family, significantly enhances regulatory T cell (Treg) frequency and suppressive function. Here, we examined the potential role and mechanism of gp96 in regulating immune-mediated hepatic injury i...

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Detalles Bibliográficos
Autores principales: Li, Xinghui, Liu, Zhen, Yan, Xiaoli, Zhang, Xiaojun, Li, Yang, Zhao, Bao, Wang, Shengdian, Zhou, Xuyu, Gao, George F., Meng, Songdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715452/
https://www.ncbi.nlm.nih.gov/pubmed/23874845
http://dx.doi.org/10.1371/journal.pone.0068997

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715452/
https://www.ncbi.nlm.nih.gov/pubmed/23874845
http://dx.doi.org/10.1371/journal.pone.0068997

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