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Endothelial Cell Permeability during Hantavirus Infection Involves Factor XII-Dependent Increased Activation of the Kallikrein-Kinin System

Hemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome (HPS) are diseases caused by hantavirus infections and are characterized by vascular leakage due to alterations of the endothelial barrier. Hantavirus-infected endothelial cells (EC) display no overt cytopathology; conseq...

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Detalles Bibliográficos
Autores principales: Taylor, Shannon L., Wahl-Jensen, Victoria, Copeland, Anna Maria, Jahrling, Peter B., Schmaljohn, Connie S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715459/
https://www.ncbi.nlm.nih.gov/pubmed/23874198
http://dx.doi.org/10.1371/journal.ppat.1003470