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Runx Transcription Factors Repress Human and Murine c-Myc Expression in a DNA-Binding and C-Terminally Dependent Manner

The transcription factors Runx1 and c-Myc have individually been shown to regulate important gene targets as well as to collaborate in oncogenesis. However, it is unknown whether there is a regulatory relationship between the two genes. In this study, we investigated the transcriptional regulation o...

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Detalles Bibliográficos
Autores principales: Jacobs, Paejonette T., Cao, Li, Samon, Jeremy B., Kane, Christyne A., Hedblom, Emmett E., Bowcock, Anne, Telfer, Janice C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715461/
https://www.ncbi.nlm.nih.gov/pubmed/23874874
http://dx.doi.org/10.1371/journal.pone.0069083