Hypoxia Modulates Fibroblastic Architecture, Adhesion and Migration: A Role for HIF-1α in Cofilin Regulation and Cytoplasmic Actin Distribution

Cells can adapt to hypoxia by various mechanisms. Yet, hypoxia-induced effects on the cytoskeleton-based cell architecture and functions are largely unknown. Here we present a comprehensive analysis of the architecture and function of L929 fibroblasts under hypoxic conditions (1% O(2)). Cells cultiv...

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Detalles Bibliográficos
Autores principales: Vogler, Melanie, Vogel, Sabine, Krull, Sabine, Farhat, Katja, Leisering, Pia, Lutz, Susanne, Wuertz, Christina M., Katschinski, Dörthe M., Zieseniss, Anke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715466/
https://www.ncbi.nlm.nih.gov/pubmed/23874890
http://dx.doi.org/10.1371/journal.pone.0069128

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715466/
https://www.ncbi.nlm.nih.gov/pubmed/23874890
http://dx.doi.org/10.1371/journal.pone.0069128

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