Inhibition of Inducible Heat Shock Protein-70 (Hsp72) Enhances Bortezomib-Induced Cell Death in Human Bladder Cancer Cells

The proteasome inhibitor bortezomib (Velcade) is a promising new agent for bladder cancer therapy, but inducible cytoprotective mechanisms may limit its potential efficacy. We used whole genome mRNA expression profiling to study the effects of bortezomib on stress-induced gene expression in a panel...

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Detalles Bibliográficos
Autores principales: Qi, Wei, White, Matthew C., Choi, Woonyoung, Guo, Charles, Dinney, Colin, McConkey, David J., Siefker-Radtke, Arlene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715471/
https://www.ncbi.nlm.nih.gov/pubmed/23874968
http://dx.doi.org/10.1371/journal.pone.0069509

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715471/
https://www.ncbi.nlm.nih.gov/pubmed/23874968
http://dx.doi.org/10.1371/journal.pone.0069509

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