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Inhibition of Inducible Heat Shock Protein-70 (Hsp72) Enhances Bortezomib-Induced Cell Death in Human Bladder Cancer Cells
The proteasome inhibitor bortezomib (Velcade) is a promising new agent for bladder cancer therapy, but inducible cytoprotective mechanisms may limit its potential efficacy. We used whole genome mRNA expression profiling to study the effects of bortezomib on stress-induced gene expression in a panel...
Autores principales: | Qi, Wei, White, Matthew C., Choi, Woonyoung, Guo, Charles, Dinney, Colin, McConkey, David J., Siefker-Radtke, Arlene |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715471/ https://www.ncbi.nlm.nih.gov/pubmed/23874968 http://dx.doi.org/10.1371/journal.pone.0069509 |
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