Synergistic Antitumor Effect between Gefitinib and Fractionated Irradiation in Anaplastic Oligodendrogliomas Cannot Be Predicted by the Egfr Signaling Activity

In high-grade gliomas, the identification of patients that could benefit from EGFR inhibitors remains a challenge, hindering the use of these agents. Using xenografts models, we evaluated the antitumor effect of the combined treatment “gefitinib + radiotherapy” and aimed to identify the profile of r...

Descripción completa

Detalles Bibliográficos
Autores principales: Pinel, Sophie, Mriouah, Jihane, Vandamme, Marc, Chateau, Alicia, Plénat, François, Guérin, Eric, Taillandier, Luc, Bernier-Chastagner, Valérie, Merlin, Jean-Louis, Chastagner, Pascal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715478/
https://www.ncbi.nlm.nih.gov/pubmed/23874590
http://dx.doi.org/10.1371/journal.pone.0068333

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715478/
https://www.ncbi.nlm.nih.gov/pubmed/23874590
http://dx.doi.org/10.1371/journal.pone.0068333

Ejemplares similares