MicroRNA-200a Regulates Grb2 and Suppresses Differentiation of Mouse Embryonic Stem Cells into Endoderm and Mesoderm

The mechanisms by which microRNAs (miRNAs) affect cell fate decisions remain poorly understood. Herein, we report that miR-200a can suppress the differentiation of mouse embryonic stem (ES) cells into endoderm and mesoderm. Interestingly, miR-200a directly targets growth factor receptor-bound protei...

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Detalles Bibliográficos
Autores principales: Liu, Yang, Liu, Qidong, Jia, Wenwen, Chen, Jie, Wang, Jianmin, Ye, Dan, Guo, Xudong, Chen, Wen, Li, Guoping, Wang, Guiying, Deng, Anmei, Kang, Jiuhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715486/
https://www.ncbi.nlm.nih.gov/pubmed/23874841
http://dx.doi.org/10.1371/journal.pone.0068990

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715486/
https://www.ncbi.nlm.nih.gov/pubmed/23874841
http://dx.doi.org/10.1371/journal.pone.0068990

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