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MicroRNA-200a Regulates Grb2 and Suppresses Differentiation of Mouse Embryonic Stem Cells into Endoderm and Mesoderm
The mechanisms by which microRNAs (miRNAs) affect cell fate decisions remain poorly understood. Herein, we report that miR-200a can suppress the differentiation of mouse embryonic stem (ES) cells into endoderm and mesoderm. Interestingly, miR-200a directly targets growth factor receptor-bound protei...
Autores principales: | Liu, Yang, Liu, Qidong, Jia, Wenwen, Chen, Jie, Wang, Jianmin, Ye, Dan, Guo, Xudong, Chen, Wen, Li, Guoping, Wang, Guiying, Deng, Anmei, Kang, Jiuhong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715486/ https://www.ncbi.nlm.nih.gov/pubmed/23874841 http://dx.doi.org/10.1371/journal.pone.0068990 |
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