Pioglitazone Improves Reversal Learning and Exerts Mixed Cerebrovascular Effects in a Mouse Model of Alzheimer’s Disease with Combined Amyloid-β and Cerebrovascular Pathology

Animal models of Alzheimer’s disease (AD) are invaluable in dissecting the pathogenic mechanisms and assessing the efficacy of potential new therapies. Here, we used the peroxisome proliferator-activated receptor gamma agonist pioglitazone in an attempt to rescue the pathogenic phenotype in adult (1...

Descripción completa

Detalles Bibliográficos
Autores principales: Papadopoulos, Panayiota, Rosa-Neto, Pedro, Rochford, Joseph, Hamel, Edith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715495/
https://www.ncbi.nlm.nih.gov/pubmed/23874687
http://dx.doi.org/10.1371/journal.pone.0068612

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715495/
https://www.ncbi.nlm.nih.gov/pubmed/23874687
http://dx.doi.org/10.1371/journal.pone.0068612

Ejemplares similares