Identification of a Novel Sulfonamide Non-Nucleoside Reverse Transcriptase Inhibitor by a Phenotypic HIV-1 Full Replication Assay

Classical target-based, high-throughput screening has been useful for the identification of inhibitors for known molecular mechanisms involved in the HIV life cycle. In this study, the development of a cell-based assay that uses a phenotypic drug discovery approach based on automated high-content sc...

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Detalles Bibliográficos
Autores principales: Kim, Tae-Hee, Ko, Yoonae, Christophe, Thierry, Cechetto, Jonathan, Kim, Junwon, Kim, Kyoung-Ae, Boese, Annette S., Garcia, Jean-Michel, Fenistein, Denis, Ju, Moon Kyeong, Kim, Junghwan, Han, Sung-Jun, Kwon, Ho Jeong, Brondani, Vincent, Sommer, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715523/
https://www.ncbi.nlm.nih.gov/pubmed/23874756
http://dx.doi.org/10.1371/journal.pone.0068767

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715523/
https://www.ncbi.nlm.nih.gov/pubmed/23874756
http://dx.doi.org/10.1371/journal.pone.0068767

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