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Identification of a Novel Sulfonamide Non-Nucleoside Reverse Transcriptase Inhibitor by a Phenotypic HIV-1 Full Replication Assay
Classical target-based, high-throughput screening has been useful for the identification of inhibitors for known molecular mechanisms involved in the HIV life cycle. In this study, the development of a cell-based assay that uses a phenotypic drug discovery approach based on automated high-content sc...
Autores principales: | Kim, Tae-Hee, Ko, Yoonae, Christophe, Thierry, Cechetto, Jonathan, Kim, Junwon, Kim, Kyoung-Ae, Boese, Annette S., Garcia, Jean-Michel, Fenistein, Denis, Ju, Moon Kyeong, Kim, Junghwan, Han, Sung-Jun, Kwon, Ho Jeong, Brondani, Vincent, Sommer, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715523/ https://www.ncbi.nlm.nih.gov/pubmed/23874756 http://dx.doi.org/10.1371/journal.pone.0068767 |
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