Cargando…
Bace1 and Neuregulin-1 cooperate to control formation and maintenance of muscle spindles
The protease β-secretase 1 (Bace1) was identified through its critical role in production of amyloid-β peptides (Aβ), the major component of amyloid plaques in Alzheimer’s disease. Bace1 is considered a promising target for the treatment of this pathology, but processes additional substrates, among...
Autores principales: | , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
European Molecular Biology Organization
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715864/ https://www.ncbi.nlm.nih.gov/pubmed/23792428 http://dx.doi.org/10.1038/emboj.2013.146 |