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Evaluating cell lines as tumour models by comparison of genomic profiles

Cancer cell lines are frequently used as in vitro tumour models. Recent molecular profiles of hundreds of cell lines from The Cancer Cell Line Encyclopedia and thousands of tumour samples from the Cancer Genome Atlas now allow a systematic genomic comparison of cell lines and tumours. Here we analys...

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Detalles Bibliográficos
Autores principales: Domcke, Silvia, Sinha, Rileen, Levine, Douglas A., Sander, Chris, Schultz, Nikolaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715866/
https://www.ncbi.nlm.nih.gov/pubmed/23839242
http://dx.doi.org/10.1038/ncomms3126