Peptide Dendrimer/Lipid Hybrid Systems Are Efficient DNA Transfection Reagents: Structure–Activity Relationships Highlight the Role of Charge Distribution Across Dendrimer Generations

[Image: see text] Efficient DNA delivery into cells is the prerequisite of the genetic manipulation of organisms in molecular and cellular biology as well as, ultimately, in nonviral gene therapy. Current reagents, however, are relatively inefficient, and structure–activity relationships to guide th...

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Detalles Bibliográficos
Autores principales: Kwok, Albert, Eggimann, Gabriela A., Reymond, Jean-Louis, Darbre, Tamis, Hollfelder, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2013
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715887/
https://www.ncbi.nlm.nih.gov/pubmed/23682947
http://dx.doi.org/10.1021/nn400343z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715887/
https://www.ncbi.nlm.nih.gov/pubmed/23682947
http://dx.doi.org/10.1021/nn400343z

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