Cargando…

P-Rex2, a Rac-guanine nucleotide exchange factor, is expressed selectively in ribbon synaptic terminals of the mouse retina

BACKGROUND: Phosphatidylinositol (3,4,5)-trisphosphate-dependent Rac Exchanger 2 (P-Rex2) is a guanine nucleotide exchange factor (GEF) that specifically activates Rac GTPases, important regulators of actin cytoskeleton remodeling. P-Rex2 is known to modulate cerebellar Purkinje cell architecture an...

Descripción completa

Detalles Bibliográficos
Autores principales: Sherry, David M, Blackburn, Bradley A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716592/
https://www.ncbi.nlm.nih.gov/pubmed/23844743
http://dx.doi.org/10.1186/1471-2202-14-70