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Cytosolic PhospholipaseA2 Inhibition with PLA-695 Radiosensitizes Tumors in Lung Cancer Animal Models

Lung cancer remains the leading cause of cancer deaths in the United States and the rest of the world. The advent of molecularly directed therapies holds promise for improvement in therapeutic efficacy. Cytosolic phospholipase A2 (cPLA(2)) is associated with tumor progression and radioresistance in...

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Detalles Bibliográficos
Autores principales: Thotala, Dinesh, Craft, Jeffrey M., Ferraro, Daniel J., Kotipatruni, Rama P., Bhave, Sandeep R., Jaboin, Jerry J., Hallahan, Dennis E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716600/
https://www.ncbi.nlm.nih.gov/pubmed/23894523
http://dx.doi.org/10.1371/journal.pone.0069688