Cargando…

Tolerogenic Vaccination Reduced Effector Memory CD4 T Cells and Induced Effector Memory Treg Cells for Type I Diabetes Treatment

BACKGROUND: Vaccination could induce immune tolerance and protected NOD mice from the development of type I diabetes (T1D). We previously demonstrated that insulin peptide (B9-23) combined with dexamethasone (DEX) stimulated the expansion of antigen specific regulatory T (Treg) cells which in turn e...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Jingyao, Gao, Wenjuan, Yang, Xu, Kang, Jingjing, Zhang, Yongliang, Guo, Qirui, Hu, Yanxin, Xia, Guoliang, Kang, Youmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716605/
https://www.ncbi.nlm.nih.gov/pubmed/23894591
http://dx.doi.org/10.1371/journal.pone.0070056